Jolanta M. Topczewska, Ph.D. 


Research Assistant Professor of Pediatrics, Northwestern University, Feinberg School of Medicine, Developmental Biology Program

2300 Children's Plaza
Box 204 Room C.421.F
Chicago, IL 60614
Phone: (773) 755-6545
Fax: (773) 755-6385 










Institute of Biochemistry and Biophysics, Polish Academy of Science, Warsaw, Poland



Warsaw University , Warsaw , Poland


Work Experience






2003 - Present 

Research Assistant Professor 

Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Children's Memorial Research Center


2003 - 2003 

Research Associate with Dr. Bruce Appel 

Department of Biological Sciences, Vanderbilt University, Nashville, TN


1998 - 2002 

Research Associate with Dr. Brigid Hogan 

Howard Hughes Medical Institute Vanderbilt University Medical Center, Nashville, TN


1996 - 1997 

Postdoctoral Fellow with Dr. Magdalena Fikus 

Institute of Biochemistry and Biophysics, PAS, Warsaw , Poland


Lab Affiliations


Topczewski lab


Recent Publications


McFarland KA, Topczewska JM, Weidinger G, Dorsky RI, Appel B (June, 2008). Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum. Developmental Biology: 162-71.

Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J and Hendrix MJC (August, 2006). Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med: 925 - 932.

Shin, J., Park, H.-C., Topczewska, J.M., Mawdsley, D.J., and Appel, B. (September, 2003). Neural cell fate analysis in zebrafish using olig2 BAC transgenics.. Meth. Cell Sci.: 7-14.

Topczewska, J.M., Topczewski, J., Szostak, A., Solnica-Krezel, L., and Hogan, B.L.M. (May, 2003). Developmentally regulated expression of two members of the Nrarp family in zebrafish.. Gene Expr. Patterns: 169-171.

Topczewska, J.M., Topczewski, J., Shostak, A., Kume, T., Solnica-Krezel, L., and Hogan, B.L. (September, 2001). The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.. Genes Dev: 2483-2493.

Kume, T., Jiang, H., Topczewska, J.M., and Hogan, B.L. (September, 2001). The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cadiovascular development and somitogenesis.. Genes Dev: 2470-2482.

Topczewska, J.M., Topczewski, J., Solnica-Krezel, L., and Hogan, B.L. (February, 2001). Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors.. Mech Dev: 343-347.


Professional Service


2005 - Present Member, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine




Zebrafish Information Network 


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