CMRC Children's Memorial Research Center

Alexandre de Andrade
 Post Doctoral Associate, Cancer Biology and Epigenomics Program

2300 Children's Plaza
Box 220 Room C.557
Chicago, IL 60614
Phone: (773) 880-4000 ext 57409
Fax: (773) 755-6551

Year Degree Institution
2005 PhD in Biochemistry Universidade of Sao Paulo
2000 Bachelor's in Chemistry Universidade of Sao Paulo

Work Experience
Period Description Organization
January 2006 - Present Post Doctoral Associate Children's Memorial Research Center, Department of Cancer Biology and Epigenomics
2001 - 2006 Chemistry teacher Curso Destaque
1996 - 1998 Chemistry teacher Delta Curso Universitario

Recent Publications
Siviero, F.; Rezende-Teixeira, P.; Andrade, A.; Machado-Santelli, G.M.; Santelli, R.V. (2006). Analysis of Expressed Sequenced Tags from Rhynchosciara americana Salivary Glands. Insect Molecular Biology: 109-118.

Andrade, A.; Teixeira, P. R.; Siviero, F.; Santelli R. V. (2005). A Shortcut in Phage Screening Technique. Genetics and Molecular Biology: 150-151.

Andrade, A.; Namora, S. F.; Woisky, R. G.; Weizel, G.; Najjar, R.; Sertiť, J. A. A.; Silva, D. O. (2000). Synthesis and Characterization of a Diruthenium-Ibuprofenato Complex Comparing its Anti-inflammatory Activity with that of a Copper(II)-Ibuprofenato Complex. Journal of Inorganic Biochemistry: 23-27.

2000- 2005 - National Council for Scientific and Technological Development (CNPq) Ph.D. fellowship in Brazil

Alexandre attended the University of S„o Paulo in Brazil where he got a bachelorís degree in Chemistry. During this time, he spent four years working in a laboratory that studied bioinorganic chemistry. There he worked on synthesizing and studying the interactions of dimetalic units of ruthenium and copper compounds and their potential roles as anti-inflammatory drugs. As a graduate student he performed research on the DNA amplification of the polytene chromosomes of the fly, Rhynchosciara americana. He focused on heat shock family genes, involved in the folding of proteins synthesized during a period concomitant with DNA amplification.

Currently, Alexandre is a post doctoral associate in Dr. Soares' lab where he is working on integrated analysis of the genome, epigenome, and transcriptome in normal and cancer cells. Ultimately, his work will generate a genome landscape of hypo- and hyper-methylated regions. This will be obtained using DNA extracted from normal and tumor tissues. The comparison of both landscapes will also identify regions of chromosomal rearrangements including deletions, duplications, and inversions.

Last Updated: Jun 27 2007 12:57PM

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