CMRC Children's Memorial Research Center
Profile


Xiaobin Wang MD, MPH, ScD
  Director and Mary Ann & J. Milburn Smith Research Professor , Child Health Research




Recent Publications
Wang L, Wang X, Wang W, Chen C, Ronnenberg A, Xu X (In Press). Stress and dysmenorrhea: A population based prospective study. Occupational and Environmental Medicine.

Wang L, Wang X, Wei LJ, Xu Xin, Xu X. (In Press). Polymorphism in maternal LRP8 gene is associated with fetal growth.. American Journal of Human Genetics.

Kumar R, Wang B, Wang X, Chen C, Yang J, Fu L, Xu X. (In Press). Bronchodilator Responses in Chinese Children from Asthma Index Families and the General Population. . Journal of Allergy & Clinical Immunology .

Wang L, Feng Y, Zhang Y, Zhou H, Jiang J, Niu T, Wei LJ, Xu Xin, Xu X, Wang X. (In Press). Prolylcarboxypeptidase Gene, Chronic Hypertension, and Risk of Preeclampsia.. American Journal of Obstetrics and Gynecology .

Perry MJ, Ouyang F, Venners SA, Korrick S, Xu X, Wang X. (In Press). A Prospective Study of Serum DDT Levels and Progesterone and Estrogen Across Menstrual Cycle in Nulliparous Women of Reproductive Age. . American Journal of Epidemiology .

Wang X, Demirtas H, Xu X. (In Press). B-Vitamin Interventions for Cardiovascular Diseases: Questions Remain. . New England Journal of Medicine .

Li J, Wang X, Huo Y, Niu T, Chen C, Zhu G, Huang Y, Xu X (2005). PON1 polymorphism, diabetes mellitus, obesity, and risk of myocardial infarction. Genetics in Medicine : 7:58-63.

Hao K, Wang X (2005). Incorporating individual error rate into association test of unmatched case-control design. Human Heridity : 58(3-4):154-63.

Venners SA, Xu X, Chen C, Guang W, Huang A, Korrick S, Altshul L, Perry M, Fu L, Wang X. (2005). Preconception Serum DDT and Pregnancy Loss: A Prospective Study Using a Biomarker of Pregnancy.. American Journal of Epidemiology : 62:878-884.

Ouyang F, Perry M, Venners SA, Chen C, Korrick S, Altshul L, Xu X, Wang X. (2005). Serum DDT, Age at Menarche, and Abnormal Menstrual Cycle Length. . Occupational and Environmental Medicine : 62:878-884. .

Jiang S, Mao G, Zhang S, Hong X, Tang G, Li Z, Liu X, Zhang Y, Wang B, Xu X, Wang X. (2005). Modification effect of the α1A-Adrenergic receptor Arg347Cys polymorphism on blood pressure response to Irbesartan treatment by plasma drug concentration in Chinese hypertensive adults.. Clinical Pharmacology and Therapeutics : 78(3):239-48. .

Perry MJ, Ouyang F, Venners SA, Chen C, Korrick S, Altshul L, Xu X, Wang X. (2005). Age, birth year, BMI, and serum DDT in nulliparous Chinese women. . Cancer Epidemiology, Biomarkers and Prevention : 14:2433-8..

Hao K, Xu X, Laird N, Wang X, Xu X (2004). Power estimation of multiple SNP association test of case-control study and application. Genetic Epidemiology. 26: 22-30.

Hao K, Wang X, Niu T, Xu X, Li A, Chang W, Wang L, Li G, Xu X (2004). A candidate gene study of preterm delivery: Application of high-throughput genotyping technology and advanced statistical methods. Human Molecular Genetics. 13: 683-691.

Venners SA, Wang X, Chen C, Wang L, Chen D, Guang W, Huang A, Ryan L, O’Connor J, Lasley B, Overstreet J, Wilcox A, Xu X (2004). Paternal smoking and early pregnancy loss: A prospective study using biomarker. American Journal of Epidemiology. 159(10): 993-1001.

Ronnenberg AG, Wood RJ, Wang X, Xing H, Chen C, Chen D, Guang W, Huang A, Wang L, Xu X (2004). Preconception Hemoglobin and Ferritin status and outcomes in a prospective cohort of Chinese women. Journal of Nutrition : 134:2586-2591.

Wang X, Mensinga TT, Schouten JP, Rijcken B, Weiss ST (2004). Determinants of maximally attained level of pulmonary function. American Review of Respiratory and Critical Care Medicine: 169:941-949.

Wang X, Chen C, Wang L, Chen D, French J, Huang A, Cho S, Liu X, Ryan L, O’Connor J, Lasley B, Overstreet J, Christiani D, Wilcox A, Xu X (2003). Conception, fetal loss, and time to pregnancy: A population based prospective study. Fertility and Sterility. 79: 577-584.

Ronnenberg AG, Wang X, Xing H, Chen C, Chen D, Guang W, Huang A, Wang L, Ryan L, Xu X (2003). Preconception body mass index is associated with birth outcome in a prospective cohort of Chinese women. Journal of Nutrition. 133: 3449-55.

Wang X, Zuckerman B, Pearson C, Kaufman G, Chen C, Wang G, Niu T, Wise P, Bauchner H, Xu X (2002). Maternal cigarette smoking, metabolic gene polymorphism, and infant birthweight. Journal of the American Medical Association. 287: 195-202.

Wang X, Zuckerman B, Kaufman G, Wise P, Hill M, Niu T, Ryan L, Xu X (2001). Molecular epidemiologic study of preterm delivery: Methodology and challenges. Paediatric and Perinatal Epidemiology. 15(supp 2): 63-77.

Chen C, Wang X, Cho SI, Chen D, Li G, Ronnenberg A, Christiani DC, Watanabe H, Xu X (2001). Tofu consumption and blood lead levels in Chinese young adults. American Journal of Epidemiology. 153: 1206-12.

Venners SA, Wang X, Chen C, Wang B, Ni J, Jin Y, Yang J, Fang Z, Xu X (2001). Exposure-response relationship between paternal smoking and children's pulmonary function. American Review of Respiratory and Critical Care Medicine. 164: 973-6.

Wang X, Chen D, Niu T, Wang Z, Ryan L, Smith T, Christiani D, Zuckerman B, Xu X (2000). Genetic susceptibility tobenzene and shortened gestation: Evidence of gene-environment interaction. American Journal of Epidemiology. 152: 693-700.

Wu D, Wang X, Chen D, Niu T, Ni T, Liu X, Xu X (2000). Metabolic gene polymorphisms and risk of dysmenorrhea. Epidemiology. 11: 648-653.

Biography
Dr. Wang is a molecular epidemiologist whose work unites molecular biology, population genetics, clinical medicine, and epidemiology and brings together laboratory science and child health professionals from multiple disciplines. Her research has covered a broad scope of child health issues ranging from adverse reproductive outcomes, child growth and development, allergy and respiratory health, and childhood precursors of adult diseases, including obesity and metabolic syndrome. Dr. Wang has authored and co-authored over 60 publications in peer-reviewed scientific journals, and many of them appear in prestigious journals, including New England Journal of Medicine and Journal of American Medical Association. She has served as scientific grant reviewer for National Institute of Health and scientific journal reviewers for over a dozen of scientific journals. She has served as a member of Institute of Medicine Committee on Understanding Premature Birth and Assuring Healthy Outcomes.

At present, Dr. Wang is the principal investigator of multiple large-scale molecular epidemiological studies, with a particular focus on a broad range of environmental factors, genetic factors, and the interaction between genes and the environment on adverse reproductive outcomes, food allergy and related conditions, and obesity and metabolic syndrome. Her work has been supported by grants from the National Institutes of Health and foundations, including March of Dimes Birth Defect Foundation and Food Allergy Project.

Dr. Wang received her MD from Beijing Medical University in Beijing, China, and a master of public health from the School of Public Health and Tropical Medicine at Tulane University in New Orleans. She also received a doctor of science degree from the Department of Maternal and Child Health at the Johns Hopkins University School of Hygiene and Public Health in Baltimore. Dr. Wang completed a three-year research fellowship in Environmental Epidemiology at the Harvard University School of Public Health and a residency in pediatrics at Boston Medical Center.


Last Updated: May 26 2006 12:35PM

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