Tyler Schwend

T Schwend

Northwestern University
Integrated Graduate Program

Laboratory of Dr. Sara Ahlgren
Developmental Biology Program
2430 N. Halsted St, Rm C-403
Chicago, IL 60614

BS, University of Illinois, Urbana-Champagne

I use the zebrafish to model two human birth defects: Holoprosencephaly and Niemann Pick Type C Disorder, disorders that can be attributed to genetic disruption of Sonic Hedgehog (shh) and Neimann Pick 1 (npc1) genes, respectively. My research seeks to understand the early progression of these disease states, especially with respect to craniofacial and brain development.

Publications:
Loucks E, Schwend T, Ahlgren SC. (2007) Molecular changes associated with teratogen-induced cyclopia. Birth Defects Research A: Clinical and Molecular Teratology. 79: 642-651.

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