CMRC Children's Memorial Research Center
Angela Hess


Angela R Hess
 Research Assistant Professor, Cancer Biology and Epigenomics Program



2300 Children's Plaza
Box 222 Room C.473
Chicago, IL 60614
Phone: (773) 755-6327
Fax: (773) 755-6594


Education
Year Degree Institution
2002 Ph.D. Department of Anatomy and Cell Biology, Univesity of Iowa, Iowa City, IA
1998 B.S. Microbiology Pennsylvania State University, University Park, PA

Dissertation
Year Title  
2002 Molecular Dissection of Melanoma Tumor Cell Vasculogenic Mimicry

Work Experience
Period Description Organization
2004 - 2005 Research Scientist Children's Memoral Research Center, Chicago, IL
2002 - 2004 Postdoctral Fellow The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA

Recent Publications
Hess, A.R, Seftor, E.A, Gruman, L.M, Kinch M.S, Seftor, R.E.B, and Hendrix, M.J.C. (2006). Ve-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry. Cancer Biology and Therapy: 224-233.

Hess, A.R, and Hendrix, M.J.C. (2006). Focal Adhesion Kinase signaling and the aggressive melanoma phenotype. Cell Cycle: 478-480.

Hess, A.R, Postovit, L.M, Seftor, E.A, Margaryan, N.V, Schneider, G.B, Seftor, R.E.B, and Hendrix, M.J.C. (2005). Focal Adhesion kinase promotes an aggressive melanoma phenotype. Cancer Research: 9851-9860.

Hess, A.R, Seftor, E.A, Seftor, R.E.B, Seftor, and Hendrix, M.J.C. (2003). Phosphoinositide 3-kinase regulates MT1-MMP and MMP-2 activity during melanoma vasculogenic mimicry. Cancer Research: 4757-4762.

Hendrix, M.J.C, Seftor, E.A, Hess, A.R, and Seftor, R.E.B. (2003). Vasculogenic Mimicry and tumour-cell plasticity: lessons from melanoma. Nature Cancer Reviews: 411-421.

Hess, A.R, Seftor, E.A, Gardner, L.M.G, Carles-Kinch, K, Schneider, G.B, Kinch, M.S, Seftor, R.E.B, and Hendrix M.J.C. (2001). Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase. Cancer Research: 3250-3255.

Maniotis, A.J, Folberg, R, Hess, A.R, Seftor, E.A, Gardner, L.M.G, Pe'er, J, Trent, J.M, Meltzer, P.S, and Hendrix, M.J.C. (1999). Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. American Journal of Pathology: 739-752.

Awards/Honors
2003 - Finalist for UMI Dissertation Award sponsored by the National Council of Graduate Schools

2003 - Received the D.C. Spriestersbach Dissertation Prize for Biological and Life Sciences, U. of Iowa

2002 - Received Travel Award from American Assoictiation of Anatomist to attend EB meeting

2001 - Selected to attend AACR special workshop; "Pathobiology of Cancer"

2000 - Received Tung-Yang Wing award for superior acheivement in Anatomy Graduate Education, U. of Iowa

1999 - Electron Microscopy Techniques presentation award, U. of Iowa

1997 - Recipient of Biochemistry and Molecular Biology Research Award; Pennsylvania State University


Curriculum Vitae
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Last Updated: Apr 5 2006 11:11AM

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