Human Molecular Genetics Program

Many of the most devastating and intractable diseases are caused by genetic defects. Errors or variations in single genes (monogenic diseases) or in multiple genes (polygenic diseases) can predispose to the disease process. The contribution of the Human Genome Project to our knowledge of gene sequences and structure has been immense. However, the availability of this tremendous knowledge base generates new challenges: to elucidate the function and regulation of genes, to establish how genetic errors cause disease, and most importantly, to translate these advances into innovative and effective therapies. The Human Molecular Genetics Program strives to nurture a world class centre of translational genetic medicine, with innovative basic science generating new routes to therapy for inherited diseases. Building on the existing scientific strengths within the program, we are recruiting additional outstanding young investigators committed to furthering the understanding of the molecular mechanisms underlying human genetic disease and designing creative approaches to novel therapies. We benefit greatly from close collaboration with other CMRC programs, in particular Developmental Biology; Cancer Biology and Epigenomics; and Neurobiology. We are also an integral part of the Northwestern University Genetics community.

Current Investigators in the Human Molecular Genetics Program include:

Christine DiDonato, Ph.D.

Ann Harris, Ph.D. (Program Director)

Laura Herzing, Ph.D.

Michael Kluppel, Ph.D.

Jill Morris, Ph.D.

Christopher Payne, Ph.D.

For more information about the Human Molecular Genetics program, please see this story from the Fall 2008 issue of InTouch.


We encourage inquiries from any members of the Children's Memorial Hospital and Northwestern communities who wish to discuss Human Molecular Genetics related projects. Please contact the relevant investigator or Chris Pomeroy (Administrative Assistant) at .

For more information about Human and Molecular Genetics contact:

Chris Pomeroy
Senior Administrative Assistant
Program in Human and Molecular Genetics
Children's Memorial Research Center
2300 Children's Plaza, no. 211
Chicago, IL 60614-3394

773-755-6345 fax