CMRC Children's Memorial Research Center

Walterhouse, D.O., Ahmed, M., Slusarski, D., Kalamaras, J., Boucher, D., Holmgren, R., and Iannaccone, P.,  gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development.  Dev. Dynamics 196: 91-102, 1993.

Jan, E., Yoon, J.W., Walterhouse, D.O., Iannaccone, P., Goodwin, E.B., Conservation of the C.elegans tra-2 3’UTR translational control.  EMBO J., 16:6301-6313, 1997.

Yang, J-T., Liu, C-Z., Villavicencio, E., Yoon, J.W., Walterhouse, D.O., and Iannaccone, P.,  Expression of human GLI in mice results in failure to thrive, early death, and patchy Hirschprung-like gastrointestinal dilatation. Molecular Medicine, 3:826-835, 1997.

Dwivedi, R.S., and Iannaccone, P.M., Effects of Environmental Chemicals on Early Development. In: Reproductive and Developmental Toxicology, Ed. Korach, K., Marcel Decker, Inc., New York, pp.11-46, 1998.

Yoon, J. W., Liu, C-Z., Yang, J-T., Mino, R., Iannaccone, P., and Walterhouse, D.O., GLI activates transcription through a VP16 like domain. J. Biol. Chem. 273(6):3496-3501, 1998

Liu, C-Z., Yang, J-T., Yoon, J.W., Villavicencio, E., Pfendler, K., Walterhouse, D.O., and Iannaccone, P., Characterization of the promoter region and genomic organization of GLI; a member of the Sonic hedgehog-Patched signaling pathway. Gene, 209: 1-11, 1998.

Walterhouse, D.O., Yoon, J.W., Iannaccone, P.,  Developmental Pathways: Sonic Hedgehog-Patched-GLI. Environ. Health Perspect. 107:167-171, 1999

Pfendler, K., Yoon, J.W., Taborn, G., Kuehn, M.R., and Iannaccone, P., Nodal and BMP-5 interact in murine mesoderm formation and implantation. Genesis: J. of Genetics and Development  28:1-14, 2000.

Villavicencio E., Walterhouse D.O., and Iannaccone P., The Sonic hedgehog-Patched-Gli pathway in human development and disease. Am. J. Human Genetics 67:1047-1054, 2000.

Kroft, T., Patterson, J., Yoon, J.W., Doglio, L., Walterhouse, D.O., Iannaccone, P., and Goldberg, E. GLI1 localization in the germinal epithelial cells Alternates between cytoplasm and nucleus; Upregulation in transgenic mice blocks spermatogenesis in pachytene. Biol.of Reprod. 65:1663-1671, 2001.

Ma, G.T., Soloveva, V., Tzeng S.J., Lowe, L.A., Pfendler, K., Iannaccone, P., Kuehn, M.R., and Linzer, D.I.H., Nodal regulates trophoblast differentiation and placental development. Dev. Biol. 236:124-35, 2001.

Iannaccone P.,     Toxicogenomics: "the call of the wild chip". Environ Health Perspect. 109:A8-11, 2001.

Yoon J., Kita Y., Frank D., Majewski R., Konicek B., Nobrega M., Patterson J., Jacob H., Walterhouse, D.O., and Iannaccone P.,  Gene expression profiling leads to identification of GLI1 binding elements in target genes and a role for multiple downstream pathways in GLI1 induced cell transformation. J. Biol. Chem. 277:5548-5555, 2002.