CMRC Children's Memorial Research Center
Marcelo B. Soares, Ph.D.

Marcelo Bento Soares
 Professor of Pediatrics, Northwestern University's Feinberg School of Medicine
Rachelle and Mark Gordon Endowed Prof and Director CBE Program, Children's Memorial Research Center

2300 Children's Plaza
Box 220 Room C.575
Chicago, IL 60614
Phone: (773) 755-6378
Fax: (773) 755-6551

Year Degree Institution
1987 Post-doctoral Columbia University, New York, NY
1986 Ph.D. with distinction Columbia University, New York, NY
1982 M.S. Federal University of Rio de Janeiro (Brazil)
1978 B.S. Federal University of Rio de Janeiro (Brazil)

Work Experience
Period Description Organization
2006 - Present Scientific Director, Falk Brain Tumor Center Children’s Memorial Hospital, Chicago, IL
2005 - Present Professor of Pediatrics Northwestern University’s Feinberg School of Medicine, Chicago, IL
2005 - Present Director, Cancer Biology & Epigenomics Program Children’s Memorial Research Center, Chicago, IL
2006 - 2007 Director, Graduate and Postgraduate Training Program Children’s Memorial Research Center, Chicago, IL
2002 - 2005 Professor of Pediatrics, Physiology & Biophysics, Biochemistry, Orthopaedics The University of Iowa, IA
2001 - 2002 Professor of Pediatrics, Physiology & Biophysics, and of Biochemistry The University of Iowa, IA
1998 - 2001 Associate Professor of Pediatrics and Physiology & Biophysics, with tenure The University of Iowa, IA
1997 - 1998 Associate Professor of Pediatrics and Physiology & Biophysics The University of Iowa, IA
1996 - 1997 Associate Professor of Neuroscience (in Psychiatry), with tenure Columbia University, NY
1994 - 1997 Research Scientist V New York State Psychiatric Institute, NY
1989 - 1996 Assistant Professor of Neurogenetics (in Psychiatry) Columbia University, NY
1987 - 1989 Assistant Professor University of Sao Paulo, Brazil

Recent Publications
Bonnet A., Iannuccelli E., Hugot K, Benne F., Bonaldo MF., Soares M.B., Hate F., Tosser-Klopp G. (January, 2008). A pig multi-tissue normalised cDNA library: large-scale sequencing, cluster analysis and 9K micro-array resource generation. BMC Genomics: 9:17.

Yamasaki C, Murakami K, et al. (January, 2008). The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Research: 36(Database issue):D793-9.

Postovit, L-M., Costa, F.F., Bischof, J.M., Seftor, E.A., Wen, B., Seftor, R.E.B., Feinberg, A.P., Soares, M.B. and Hendrix, M.J.C. (July, 2007). The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. J Cell Biochem: 101(4):908-17.

Reyes-Prieto, A., Hackett, J.D., Soares, M.B., Bonaldo, M.F. and Bhattacharya, D. (December, 2006). Cyanobacterial contribution to algal nuclear genomes is primarily limited to plastid functions. Current Biology: 16: 2320-2325.

Chun, C, Scheetz, T, Bonaldo, M, Brown, B, Clemens, A, Crookes-Goodson, W, Crouch, K, DeMartini, T, Eyestone, M, Goodson, M, Janssens, B, Kimbell, J, Koropatnick, T, Kucaba, T, Smith, C, Stewart, J, Tong, D, Troll, J, Webster, S, Winhall-Rice, J, Yap, C, (June, 2006). An annotated cDNA library of juvenile Euprymna scolopes with and without colonization by the symbiont Vibrio fischeri. BMC Genomics: 7:154.

Segal, J.P., Stallings, N.R., Lee, C.E., Zhao, L., Socci, N.D., Viale, A., Harris, T.M., Soares, M.B., Childs, G., Elmquist, J., Parker, K.L. and Friedman, J.M. (April, 2005). Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. Journal of Neuroscience: 25(16): 4181-4188.

Wang, D., Huang, J., Xie, H., Manzella, L. and Soares, M.B. (January, 2005). A robust two-way semi-linear model for normalization of cDNA microarray data. BMC Bioinformatics: 6(1): 14.

Bonaldo, M., Bair, T., Scheetz, T., Snir, E., Akabogu, I., Bair, J., Berger, B., Crouch, K., Davis, A., Eyestone, M., Keppel, C., Kucaba, T., Lebeck, M., Lin, J., Melo, A., Rehmann, J., Reiter, R., Schaefer, K., Smith, C., Tack, D., Trout, K., Sheffield, (October, 2004). 1,274 full-open reading frames of transcripts expressed in the developing mouse nervous system. Genome Research: 14: 2053-2063.

Gerhard DS, Wagner L, Feingold EA, et al. (October, 2004). The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Research: 14(10B):2121-7.

Imanishi, T., Itoh, T., et al. (June, 2004). Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PloS Biol.: 2(6): E162.

Laffin, J.J.S., Scheetz, T.E., Bonaldo, M.F., Reiter, R.S., Chang, S., Eyestone, M., Abdulkawy, H., Brown, B., Roberts, C., Tack, D., Kucaba, T., Lin, J.J-C., Sheffield, V.C., Casavant, T.C., and Soares, M.B. (April, 2004). A comprehensive nonredundant expressed sequence tag collection for the developing Rattus norvegicus heart. Physiol. Genomics: 17: 245–252.

Scheetz, T.E., Laffin, J.J., et al. (April, 2004). High-throughput gene discovery in the rat. Genome Research: 14: 733-741.

Scheetz, T.E., Zabner, J., Welsh, M.J., Coco, J., Eyestone, M., Bonaldo, M.F., Kucaba, T., Casavant, T.C., Soares, M.B., and McCray, P.B. (March, 2004). Large-scale gene discovery in human airway epithelia reveals novel transcripts. Physiol. Genomics: 17: 69-77.

Verjovski-Almeida, S., DeMarco, R., et al. (October, 2003). Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni. Nature Genetics: 35(2):1-10.

Strausberg, R.L, Feingold, E. A., et al. (December, 2002). Generation and Initial Analysis of more than 15,000 Full-Length Human and Mouse cDNA Sequences. Proc. Natl. Acad. Sci. USA: 99(26):16899-903.

2006 – 2007 - Rachelle & Mark Gordon Endowed Prof in CBE Hope Award, Bear Necessities Pediatric Cancer Foundation

2001 - Leadership Award, University of Iowa Macular Degeneration Center

1987 – 1989 - Career Development Fellowship Award from the Brazilian National Research Council

1982 – 1986 - Scholarship for Graduate Studies (Ph.D. degree), LASPAU and the Brazilian National Research Council

1979 – 1982 - Scholarship for Graduate Studies (Master of Science degree), Brazilian National Research Council

1977 – 1979 - Scholarship for Undergraduate Research, Brazilian National Research Council

Editorial Boards
Period Description
2008 - Present Member, Gene
1999 - Present Member, Functional and Integrative Genomics
1998 - Present Member, Physiological Genomics
1996 - 2007 Member, Genome Research

Professional Service
2005 - Present Society for Neuroscience
2003 - Present Member, American Association for Cancer Research
2001 - Present Co-Founder TRANSCRIPTOME Conference Series
2000 - Present Member, Steering Committee, Korean Genome Project
1999 - Present Member, Steering Committee, Ludwig Cancer Institute/FAPESP Human Cancer Genome Program
1998 - Present Organizer, Banbury Center Meeting: “Full-length cDNA Cloning: A Workshop on Problems and Solutions”, Cold Spring Harbor, NY, March 23rd-25th.
1995 - Present Member, American Society of Human Genetics
1994 - Present Member, Human Genome Organization
1993 - Present American Association for the Advancement of Science
1992 - Present Founder, Integrated Molecular Analysis of Gene Expression (I.M.A.G.E.) Consortium
1994 - 1998 Member, Genome Study Section/National Center for Human Genome Research/NIH

Curriculum Vitae