CMRC Children's Memorial Research Center
Why use zebrafish as a model?

Genetic accessibility
   Small, cheaply maintained
   Lay hundreds of eggs at weekly intervals
   Short generation time 2-3 months
   Easy to perform large scale forward-genetic analysis

Experimental accessibility
   Externally fertilized
   Accessible to observation and manipulation from the moment of    fertilization
   Manipulation of gene activity by oligonucledide, RNA and DNA injection
   Generation of transgenic animals

Optical transparency
   Fate mapping
   Fluorescent tracer time-lapse lineage analysis
   Single cell transplantation

To learn more about research using zebrafish go to:
The Zebrafish Information Network web site.